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| Thursday, September 02, 2010 |
| TBA - Florida A&M at Miami-FL |
| TBA - E. Washington at Nevada |
| 6:30pm - PRESBYTERIAN at Wake Forest |
| 7:00pm - Murray St. at Kent State |
| 7:00pm - Hampton at Central Michigan |
| 7:00pm - SE Missouri St. at Ball State |
| 7:00pm - Rhode Island at Buffalo |
| 7:30pm - Minnesota at Middle Tenn. |
| 7:30pm - Southern Miss. at South Carolina - ESPN |
| 7:30pm - Marshall at Ohio State - Big Ten Network |
| 7:30pm - Towson at Indiana - Big Ten Network |
| 7:30pm - Norfolk St. at Rutgers |
| 8:00pm - Florida Atlantic at UAB |
| 8:00pm - SE Lousiana at Tulane |
| 8:00pm - Northern Illinois at Iowa State - FSN-MW |
| 8:30pm - Pittsburgh at Utah - Versus |
| 9:00pm - NORTH DAKOTA at Idaho |
| 11:00pm - USC at Hawaii - ESPN |
| Friday, September 03, 2010 |
| 5:00pm - Villanova at Temple |
| 8:00pm - Arizona at Toledo |
| Saturday, September 04, 2010 |
| TBA - STONY BROOK at South Florida |
| TBA - Florida Atlantic at UAB |
| TBA - SOUTH DAKOTA at UCF |
| 12:00pm - Miami-OH at Florida - ESPN |
| 12:00pm - Youngstown St. at Penn State |
| 12:00pm - Western Michigan at Michigan State |
| 12:00pm - Samford at Florida State - ESPNU |
| 12:00pm - Eastern Illinois at Iowa - Big Ten Network |
| 12:21pm - Louisiana-Laf. at Georgia |
| 12:30pm - Missouri at Illinois |
| 1:00pm - Weber State at Boston College |
| 1:00pm - South Carolina St. at Georgia Tech |
| 2:00pm - Northwestern St. at Air Force |
| 2:00pm - Colorado at Colorado State - MTN |
| 3:30pm - Texas at Rice |
| 3:30pm - Jacksonville St. at Ole Miss |
| 3:30pm - New Mexico at Oregon |
| 3:30pm - Kentucky at Louisville |
| 3:30pm - Purdue at Notre Dame - NBC |
| 3:30pm - UCLA at Kansas State |
| 3:30pm - North Texas at Clemson - ESPNU |
| 3:30pm - Coastal Carolina at West Virginia |
| 3:30pm - Connecticut at Michigan |
| 5:00pm - UC Davis at California |
| 6:00pm - Tennessee Martin at Tennessee |
| 6:00pm - Richmond at Virginia |
| 6:00pm - Western Carolina at NC State |
| 6:00pm - Syracuse at Akron |
| 7:00pm - Western Kentucky at Nebraska - PPV |
| 7:00pm - Wash. St. at OK State - FSN |
| 7:00pm - NO DAKOTA ST at Kansas |
| 7:00pm - Memphis at Miss. State - ESPNU |
| 7:00pm - Arkansas St. at Auburn |
| 7:00pm - San Jose St. at Alabama |
| 7:00pm - Stephen F. Austin at Texas A&M |
| 7:00pm - Utah State at Oklahoma |
| 7:00pm - Sam Houston St. at Baylor |
| 7:00pm - Army at Eastern Michigan |
| 7:00pm - Grambling at Louisiana Tech |
| 7:00pm - Bowling Green at Troy |
| 7:00pm - Wofford at Ohio |
| 7:00pm - Tennessee Tech at Arkansas |
| 7:00pm - Washington at BYU |
| 7:00pm - Elon at Duke |
| 7:30am - Northwestern at Vanderbilt - CSS |
| 7:45pm - Oregon State at TCU |
| 8:00pm - Nicholls St. at San Diego St. |
| 8:00pm - Texas State Uni at Houston |
| 8:00pm - LSU at North Carolina - ABC |
| 9:00pm - Southern Utah at Wyoming |
| 6:30pm - CS Sacramento at Stanford - CSN |
| 9:05pm - Arkansas-PB at Texas-El Paso |
| 10:00pm - Cincinnati at Fresno State - ESPN2 |
| 10:00pm - Portland St. at Arizona State |
| 11:00pm - Wisconsin at UNLV |
| Sunday, September 05, 2010 |
| 2:00pm - Tulsa at East Carolina - ESPN2 |
| 3:30pm - SMU at Texas Tech |